Abstract:The incidence of skin tumors in canine is often influenced by breed and age.They are more common in elderly and rarely seen in growing dogs,especially in growing Beagles.This article reports a case of spontaneous tumor in a beagle during the growing period,and conducts tissue sampling,pathological staining analysis and identification.Hematoxylin-eosin staining of the tumor tissue revealed that the canine tumor was located in the dermis,distributed focally,and contained a large amount of eosinophilic cytoplasm with abnormal nuclear morphology.Immunohistochemical results showed that Vimentin and CK were positive,while α-SMA,KI67,S-100 and CD34 were negative.Combined with the analysis of pathological staining results,the preliminary conclusion was probably fibrous histiocytoma.This case report provides a basis for the future diagnosis of canine tumor disease and new perspective for the quality control of beagle.