Abstract:In recent years,Bovine viral diarrheal disease/mucosal disease(BVD-MD) has been widely prevalent both domestically and internationally,causing serious harm to the cattle industry.It is difficult to differentiate BVD-MD from other diarrheal diseases only by clinical symptoms and pathological changes.In order to diagnose and purify BVD-MD,it is very important to choose the best detection method.In practical applications,the choice of suitable testing methods should consider various testing purposes comprehensively.This article provides a comprehensive review of BVDV pathogens,prevalent strains,and recent advancements in detection methods to serve as a reference for epidemiological investigations,pathogenic mechanisms,detection,and prevention of bovine viral diarrhea/mucosal disease.