Abstract:In order to understand and master the infection and epidemic situation of infectious pleural pneumonia in sheep in Liangzhou District,we collected 390 sheep samples from 14 largescale sheep farms in March 2023 to carry out the serological investigation of infectious pleural pneumonia in sheep.After testing,the average positive rate of antibodies against mycoplasma infection was 6.1% in nonimmune sheep;the average positive rate of mycoplasma antibody was 75.3%;the average positive rate of antibodies against mycoplasma ovipneumoniae infection in the sheep flocks of suspected diseased farms was 78.3%.The results proved that there was mycoplasma ovipneumoniae infection in largescale farms in Liangzhou District,which should be paid attention to.This experiment provides reference for the largescale farms in Liangzhou District to develop the prevention and treatment technology of infectious pleural pneumonia in sheep,and take targeted and effective prevention and control measures.