Abstract:Sodium humate feed additive is a new green, lowcost and highefficiency additive. This has been widely studied and applied in the field of animal husbandry and veterinary medicine at home and abroad. Wuwei City’s demonstration of the application of sodium humate in the field of animal husbandry is still in its initial stage. This test was implemented in conjunction with the farm project. By adding 0.5%, 1%, 2%, and 4% sodium humate to the dietary concentrates of lambs of the same age, the antibody reduction situation was tracked and detected, and the immunity of the test lambs was understood and compared. The length of protection period, disease treatment medications, and immune function regulation. The results showed that after feeding lambs under the same management conditions, the antibody levels of lambs in each test group were significantly higher than those in the control group and the protection period was extended, with significant effects(P<0.05). At 1%, 2%, and 4%, the immune antibody level of the lamb vaccine was still above 90% at 4 months, and at 1% and 2%, the cost of drug treatment was the least, and intestinal diseases such as diarrhea were significantly improved. As the sodium humate level increased, the immune indicators of the lambs gradually improved compared with the control group, and the immunoglobulin IgG and IgA contents in the blood of the sheep gradually increased. This suggests that adding relatively high levels of sodium humate can improve sheep immune function more than low levels. Under the current new situation of promoting healthy and antibioticfree breeding in China, it can be widely promoted and applied.