Abstract:This study aims to understand the immune status of pig footandmouth disease O (FMDO) vaccine in Yuanjiang County and evaluate the immune effect. From 2018 to 2021, in largescale farms and freerange farmers in 10 townships in the county, we randomly collected pig serum samples, and used ELISA method for immune antibody detection. The results showed that the average qualified rate of FMDO immune antibody in different years was 64.94%. The average qualified rate of FMDO immune antibody in different regions was 64.01%. There was a difference of 1.62 percentage points in the qualified rate of immune antibodies in FMDO farms with different farming methods (66.23%) and freerange farmers (64.61%), and the difference was not significant (P> 0.05). The results showed that in recent years, the overall immune effect of FMDO in pigs in Yuanjiang County was not very satisfactory, and the year, region and breeding method that the immunity did not meet the standard appeared. It deserves great attention. The detection results can provide reference for potential risk point control, vaccine selection and prevention and control of pig FMDO in Yuanjiang County.