Abstract:With the rapid development of animal husbandry in my country, the difficulty of disease prevention and control is increasing, which has become an important factor restricting the healthy development of animal husbandry. Changing the traditional disease prevention and control mode and implementing disease purification are effective means to comprehensively improve the biosafety level of farms and animal disease resistance. This is an important basis for promoting the sustainable development of the aquaculture industry. In this paper, the present situation of disease purification in livestock and poultry farm was analyzed and some suggestions were put forward.