Abstract:Calf gastroenteritis is a common disease in calves. This is an inflammatory lesion of the calf's gastrointestinal mucosa and submucosal deep tissue. The disease can occur in all seasons. If the farmers are not strict with the feeding requirements and the feeding management is improper, the disease is very prone to occur. After the disease occurs, with the development of the disease, the inflammation gradually develops from the mucosal layer to the submucosa layer, muscle layer, and serosa layer, resulting in mucosal hemorrhage, edema, and even necrosis. This creates dysfunction and autotoxicity. The disease is severe and has a high mortality rate. This will bring great economic losses to farmers if the disease occurs.