禽大肠杆菌性肉芽肿病病理学诊断

Pathological Diagnosis of Avian Colibacillary Granulomatosis

摘要:

2022年8月某鸡场50多日龄鸡只出现消瘦并陆续死亡,至110日龄每天死亡率约0.2%,发病率10%左右。为诊断该场疾病,采取病理剖检、PCR/RT-PCR检测、组织病理学诊断与细菌分离鉴定的方法对病鸡进行诊断。PCR/RT-PCR检测结果为ALV、MDV、REV与HEV阴性,大肠杆菌阳性。病理剖检发现病鸡肠系膜、肾、肝、肺等部位有黄豆粒至鹌鹑蛋大小的结节,组织病理学表现为各组织特征性肉芽肿结节。通过与禽结核病、禽马立克病、禽淋巴细胞性白血病的病理学变化比较,旨在为临床诊断与鉴别诊断疾病提供材料。

Abstract:

In August 2022,50-day-old chickens in a certain chicken farm successively showed symptoms of weight lose and death,the mortality rate was about 0.2% per day,and the morbidity rate was about 10% per day until 110-day-old.Pathological dissection,PCR,RT-PCR,and qPCR detection,histopathological diagnosis,and bacterial isolation and identification were used to diagnose the diseased chicken,the results of PCR and RT-PCR were negative for ALV,MDV,REV and HEV,and positive for Escherichia coli.Pathological examination revealed nodules with size ranging from soybean seeds to quail eggs in the mesentery,kidneys,liver,lungs,and other parts of the diseased chickens,the histopathological findings showed characteristic granulomatous nodules in each tissue.By comparing pathological changes with avian tuberculosis,avian Marek's disease and avian lymphocytic leukemia,the aim is to provide materials for clinical diagnosis and differential diagnosis of diseases.