The creation of disease-free zones is in line with the national deployment requirements for the routine prevention and control of animal diseases and regional management.It can further enhance the region’s ability to prevent and control animal diseases and improve biosafety management levels,thereby opening up a new pattern for regionalized disease management.This provides an effective guarantee for the safety of livestock product quality and ecological environment.This article first summarizes the efforts made by Huishui county in the prevention and control of African swine feve.Secondly,it analyzes the key elements of the establishment and ongoing supervision of diseasefree area in Huishui county.Finally,it proposes some solutions to existing problems for reference.