Abstract:Feline panleukopenia,also known as feline plague,is an acute and highly contagious infectious disease.Cats with incomplete or unvaccinated vaccines are susceptible to feline plague,which has diverse infectious sources and high fatality rate.It is a common and harmful infectious disease in clinical practice.In this paper,the examination,diagnosis,treatment,outcome and prognosis of three cases of feline panleukopenia were discussed,and the results of laboratory examination items such as blood routine,biochemical text,infectious disease test and blood gas test were analyzed in detail,and the diagnosis was made.The treatment idea of supportive nursing and symptomatic treatment was followed,and antiviral drugs were used to treat the last two cases successfully,and one died.This article summarizes the treatment plan in detail,hoping to provide reference for future clinical diagnosis and treatment.