Abstract:The study introduces one case of acute nephritis in Garfield the cat, who exhibited reduced abdominal circumference, sensitivity and pain in the kidney area, an arched back when standing, frequent urination, but with small amounts each time.The study introduces the basic information of the case, including general clinical examination, X-ray, B ultrasound and laboratory examination and the comprehensive analysis of the result, so that we can exclude any other possible disease and eventually the cat was diagnosed with acute nephritis and doubtedly associated with pancreatitis. With rational drug use and the principle of protection of the kidney and diuresis, we take active treatment, including immunosuppression, eliminate inflammation, infection control, diuretic therapy and symptomatic treatment, and the cat recovered in ten days. The final part of the study is to have a discussion regarding the causes, diagnosis and treatment and put forward some practical suggestions on the effective treatment and Clinical medication. In conclusion, it is hoped that it will be helpful for animals with acute nephritis.