两种不同猪瘟疫苗对育肥猪的免疫效果比较

Comparison of Immunity Efficacy of Two Different Swine Fever Vaccines on Fattening Pigs

摘要:

为比较猪瘟疫苗E2基因工程亚单位疫苗和猪瘟活疫苗对育肥猪免疫效果和生产成绩的影响，以便为规模猪场在选择猪瘟疫苗时提供参考。本试验从汉中某代养场选取了一批健康的断奶仔猪分成三组，A组免疫猪瘟E2基因工程亚单位疫苗（简称E2亚单位疫苗），B组免疫猪瘟活疫苗（脾淋源），C组为对照组不做猪瘟疫苗免疫。免疫60 d后各组随机抽取10、15和12份血样用猪瘟病毒抗体检测试剂盒检测猪瘟抗体水平。结果表明接种的两种猪瘟疫苗对育肥猪的免疫效果差异极显著（P<0.01），其中E2亚单位疫苗相比于猪瘟活疫苗能够明显提高育肥猪抗体阻断率和降低离散度，并且有助于育肥猪的健康生长。

Abstract:

To compare the effects of classical swine fever E2 genetically engineered subunit vaccine and live swine fever vaccine on the immune effect and production performance of fattening pigs, so as to provide reference for large-scale pig farms when selecting swine fever vaccine. In this experiment, a batch of healthy weaned piglets were selected from a generation farm in Hanzhong and divided into three groups, group A was immune to swine fever E2 genetically engineered subunit vaccine (referred to as E2 subunit vaccine), group B was immune to live swine fever vaccine (spleen leaching source), and group C was the control group without swine fever vaccine immunization. After 60 days of immunization, 10, 15 and 12 blood samples were randomly selected from each group, and the swine fever antibody level was detected with the swine fever virus antibody detection kits. The results showed that the immune effect of the two swine fever vaccines on fattening pigs was highly significant (P<0.01), and the E2 subunit vaccine could significantly improve the antibody blocking rate and reduce the dispersion of fattening pigs compared with live swine fever vaccine, and contribute to the healthy growth of fattening pigs.