Abstract:This study was to investigate the effects of compound probiotics on the growth and immune function of weaned piglets. We selected 72 Duroc × Landrace × Yorkshire weaned piglets with similar weight and good health, and randomly divided them into 3 groups. Group Ⅰ was fed with basal diet. Group Ⅱ was fed with 0.1% compound probiotics test diet. Group Ⅲ was fed with 0.1% antibiotic test diet. The pretest period was 7 days, and the formal test period was 30 days. The results showed that compared with group Ⅰ, the daily gain of group Ⅱ and group Ⅲ increased by 24.46% and 19.01% (P< 0.05), respectively, and the ratio of feed to weight decreased by 13.04% and 12.50% (P< 0.05). The serum IgG content of group Ⅱ was 34.96% and 47.80% higher than that of group Ⅰ and group Ⅲ respectively (P< 0.05). This shows that adding compound microecological preparations to the diet of weaned piglets can increase the daily gain of weaned piglets and improve the immune function of weaned piglets.